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Audrey Burke (Halle Berry) is reeling from the shock of the news that has just been delivered to her door by the local police: her warm and loving husband Brian (David Duchovny), the father of their two young children, has been killed in a random act of violence.

Once anchored by the love and comforts of their 11-year marriage, Audrey is now adrift. Impulsively, she turns to Jerry Sunborne (Benicio Del Toro), a down-and-out addict who has been her husband’s close friend since childhood.

Desperate to fill the painful void caused by her husband’s death, Audrey invites Jerry to move into the room adjacent to their garage in the hope that he can help her and her children cope with their sudden loss. Jerry is facing a daily battle to stay off drugs, but in his unexpected role as surrogate parent and friend to Audrey’s son and daughter he finds a core of inner resilience. As Jerry and Audrey navigate grief and denial, their fragile bonds are constantly tested. Working together, however, they discover the strength to move forward.