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Helen/102818/">Helen Harris (Kate Hudson) is living the life she always dreamed of. Her career at a top Manhattan modeling agency is on the rise; she spends her days at fashion shows and her nights at the city's hottest clubs. But her carefree lifestyle comes to a screeching halt when one phone call changes everything.

Helen/102818/">Helen soon finds herself responsible for her sister's children: 15-year-old Audrey (Hayden Panettiere), 10-year-old Henry (Spencer Breslin), and 5-year-old Sarah (Abigail Breslin). No one doubts that Helen/102818/">Helen is the coolest aunt in New York, but what does this glamour girl know about raising kids?

The fun begins as Helen/102818/">Helen goes through the transformation from super hip to super mom, but she quickly finds that dancing at 3 a.m. doesn't mix with getting kids to school on time - advice that Helen/102818/">Helen's older sister, Jenny/82930/">Jenny (Joan Cusack), is only too quick to dish out.

Along the way, Helen/102818/">Helen finds support in the most unusual place - with Dan Parker (John Corbett), the handsome young pastor and principal of the kids' new school - and realizes the choice she has to make is between the life she's always loved and the new loves of her life.