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Dan (Jude Law), an aspiring novelist who earns a living writing obituaries, meets Alice (Natalie Portman), who becomes his muse. Through her, he blossoms and becomes confident enough to approach the woman he believes he's in love with, Anna (Julia Roberts), a successful photographer and recent divorcée. After meeting and flirting with Dan, Anna marries Larry (Clive Owen), a handsome, self-assured dermatologist, while carrying on a secret affair with Dan.

Based on the award-winning play by Patrick Marber.