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Jessica Martin (Kim Basinger) is a high school science teacher and mother whose peaceful life is turned upside down when she is kidnapped from her home by five unknown assailants and taken to a mysterious location. Fearful for her life and completely in the dark as to her abductors' motives, Jessica manages to patch together a shattered telephone and secretly place a call to an unknown number in a last-ditch attempt to save herself. Ryan (Chris Evans), the carefree young man who answers the panicked call, suddenly finds himself Jessica's last hope.
With no knowledge of Jessica other than her hushed, fearful voice on the other end of the tenuous phone connection, Ryan is quickly thrown into a world of deception and murder in a frantic search to find and save her. The lives of Jessica and her family are in his hands, but what is waiting for him on the other side of the line and what will it cost him to find out?