Neglecting Julie (Frances McDormand), his lawyer lady friend, Dr. Peyton Westlake (Liam Neeson) works feverishly to perfect his latest invention -- artificial skin that could be used to treat burn victims.
Peyton himself falls victim to an explosion when one of Julie's crooked clients sends his henchmen to sniff out an incriminating document that's been left in Westlake's lab.
Hideously disfigured and left for dead, the good doctor receives an experimental medical treatment that renders him super-strong, impervious to pain and prone to heightened fits of rage.
Rebuilding his lab into an underground hideout, Westlake begins using his synthetic skin to impersonate various characters and engineer his revenge against those who destroyed his life. Reconnecting with Julie, however, becomes the unsightly vigilante's biggest challenge.