An unexpected series of events turns everyday store clerk Harley into a wanted man - and even more unexpectedly, he finds himself on the run with the girl of his dreams. FBI Agent McFadden is determined to crush him and wants to teach her rookie partner how it's done.
But while the agents pursue their culprit, our hero has loftier pursuits. He kidnaps his Vietnam vet grandfather to reunite him with the love of his life, picks up a try-hard beatnik hitchhiker with a secret of his own, and against all common sense follows a roadside attractions map with a mysterious history. As the agents get closer and closer with every stop, this eclectic band of misfits becomes an unlikely family.