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Jessica (Westfeldt) is a straight, neurotic New York journalist who's tired of being single. Her best friend's pregnant, her brother's engaged, and all the guys she meets are losers. So, on a whim, she answers a personal ad -- from the "women-seeking-women" section, placed by Helen/102818/">Helen (Juergensen), a stylish art gallery owner who's also straight. Over drinks, the two discover a mutual attraction, and decide to start a romantic relationship.