In 1927, a band of angry townsfolk travel deep into the Louisiana Bayou to destroy an Satanic painter named Schweik. In an isolated Gothic hotel basement, they chain-whip, crucify, and shower the warlock in a flesh-emulsifying liquid. But they are too late. Schweik had already opened one of the seven dread gateways to Hell beneath the eerie hotel.
Many years later, Liza (Catriona MacColl) comes to Louisiana to claim her inheritance: Schweik's Seven Doors Hotel. With the help of the hotel's longtime housekeeper and her caretaker son, Liza begins renovations on the property.
But their work is plagued by bizarre and supernatural events: a normally sure footed painter falls off a scaffolding, a plumber has his eyes inadvertently poked out, an architect researching the hotel's origins is attacked by a band of blood-sucking tarantulas and, ultimately, the housekeeper is impaled on an unfortunately placed spike.